Audio problem: During the bee scene, Ron tells Amy "It's all your stupid fault", but from a side angle he's not mouthing the lines.
Sacha
Continuity mistake: When the kids exit the waste bag, from the wide angle it swaps from black to light grey. Also, the fence disappears.
Sacha Continuity mistake: After Nick falls on the pollen, there's a shot of his mom calling him. Right after, the amount of pollen on him is completely different.
Sacha Revealing mistake: When the green-screened bee passes by Ron and Russ they stare at it, but when it flies away they keep looking at the same spot as before.
Sacha Continuity mistake: When Mr. Thompson is shrunk and waves at his family, he is sitting between two bolts. When the angles changes, from a back view, he is sitting right in front of one.
Sacha Continuity mistake: When the kids are about to climb the grass, Wayne lets Quark out and the door closes twice: In the close-up and afterwards in the wide angle.
Sacha Continuity mistake: Pair of blue jeans disappear from Wayne's shoulder after he turns the faucet off.
Sacha Continuity mistake: Nick falls on the pollen on the left side of the flower. When the angle changes he's right on the middle of it.
Sacha Continuity mistake: The position of the trash bag left by Wayne differs between shots.
Sacha Continuity mistake: When Wayne is destroying the machine, the kids' position differs between the front and back angles.
Sacha Continuity mistake: When Wayne tries to shrink the apple, the way he holds the remote control differs between the close-ups and wide angles.
Sacha Continuity mistake: When the movie starts and the dog has left the letters, watch the bottles of paint in front of him: They appear closer together in the opposite angle.
Sacha Continuity mistake: From Nick's POV, he enters his father's lab and opens the door wide, yet from the opposite angle it is slightly open.
Sacha Continuity mistake: When the movie starts, and the dog brings the letters, their position on the table changes between shots.
Sacha Visible crew/equipment: When the neighbours visit the Szalinskis to get their baseball and Nick opens the door, you can see the reflection of the cameras and lights in the glass.
Sacha Continuity mistake: After the apple explodes, the amount of fruit on Wayne's forehead increases when he sits on the couch and Quark licks him.
Sacha Revealing mistake: When the (green-screened) bee arrives at the flower, the yellow pollen turns dark pink due to the blue/gree screens used.
Sacha 
Answer: More along the lines of a serious health problem related to her "plumbing".
Greg Dwyer