Deliberate mistake: In Silence of the Lambs Starling was right-handed. In Hannibal she is left handed because we see her writing with her left. Julianne Moore, the new actress who plays Starling is left handed whereas Jodie Foster was obviously right-handed.
Hannibal (2001)
1 deliberate mistake - chronological order
Directed by: Ridley Scott
Starring: Julianne Moore, Gary Oldman, Anthony Hopkins, Ray Liotta
Factual error: At the end of the film, Ray Liotta wouldn't be able to raise his eyebrows as the frontalis muscle had been divided. (01:57:10)
Mason Verger: I guess you wish now that you fed the rest of me to the dogs.
Hannibal Lecter: No Mason. No I much prefer you the way you are.
Trivia: In the brain eating scene, the piece of brain Ray Liotta eats is actually a piece of cooked chicken.
Question: Why did Paul Krendler dislike Clarice so much, and why did he ruin her career?
Answer: Starling says to Krendler "Paul, what is it with you? I told you to go home to your wife, that was wrong?", implying that he had made a pass at her and she had rejected him. He replies that it was a long time ago, and that he didn't hold it against her, but combined with Mason Verger's bribe this was most likely the cause of his antagonism towards Starling.
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Answer: In the book it says that Clarice had caught Buffalo Bill before he could. It said also that is why he hated her early in the book.