Elizabeth Masterson (Reese Witherspoon) is a work-alcoholic San Francisco doctor with no time for a life and David Abbott is a grieving widow. One fateful night will change both of their lives forever.
Dr. Masterson meddling older sister, Abby, has set her up on yet another blind dinner date at her house and has ordered her younger sister to join.
Running late and excited about a recent promotion, Elizabeth doesnt see the semi-truck coming at her head on before its too late.
David Abbott (Mark Ruffalo) has decided to rent out the cozy apartment with the comfortable couch as a place to drink himself numb to his wife's untimely death two years ago.
One night, (after some heavy drinking), he is shocked to see a woman yelling at him to get out of her apartment. It turns out to be Elizabeth, who doesnt believe she is dead, even though no one else can see her but him and she cant psychically pick anything up.
With the help of an eccentric bookseller who has the gift of reading aura's, David finds that Elizabeth isnt dead, she is too alive a spirit to be dead.
With the help of clues in her apartment and Elizabeth's shaky memory he learns that she really isnt dead, but in a coma from her accident and has some unfinished business that has enabled her to stay on Earth.
Now, he is a race aganist time and the hospital to stop them from pulling her plug and killing the woman he loves.