Continuity mistake: Dr. Klein and Dr. Taney arrive at the house and go up to Regan's room to see her for themselves. We see inside the room and the two doctors, Chris and Sharon are the only ones there but as they try to give her an injection, Karl appears from out of nowhere restraining her. (00:54:05)
Continuity mistake: When Chris is taking a walk with the priest Damien, she throws her cigarette to the ground, but in the next shot it's back in her hand again.
Trivia: In the scene where Regan's mother is supernaturally blasted away from the bedside, she is being yanked by the crew by a length of rope. After dozens of takes director William Friedkin was still unhappy with the look of the shot and ordered the crew to haul her more fiercely. The scream in the shot that made the cut was of genuine pain and required no dubbing for effect.
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