Continuity mistake: At the wrap party for "Bride of the Atom," when Dolores starts screaming at Ed "These movies are TERRIBLE!" her hair is curled in ringlets that hang down to the tops of her shoulders. She then stalks out of the warehouse, and Ed follows her. When he catches up to her in the parking lot, and she tells him she is leaving him, you can clearly see that her hair is suddenly much shorter and curlier.
Factual error: The movie is set in the late 1950s, yet Ed's car has yellow-on-black California license plates that weren't issued until 1963. The plates on Ed's car should be black-on-yellow 1956 issue plates.
Factual error: Ed Wood films Lugosi exiting his house, and grabbing a flower near the entrance, a scene to be shown in "Plan 9". However, in fact, the real scene of "Plan 9" shows Lugosi exiting his house, walking across a garage door (that doesn't exist in "Ed Wood") and grabbing a flower around there.