Continuity mistake: In the scene where Pauly Shore and Stephen Baldwin's girlfriends arrive right after Baldwin is smacked in the face with the encyclopedia, Baldwin is shown lying on the ground directly above his face, and off to the side. When the camera is off to the side, his braids are in his face, but when they are directly above him, his braids have been brushed away.
Continuity mistake: As the professor is showing Bud and Doyle around the Bio-Dome he takes them onto a raised platform. From the wide shot we see that his scarf is not on properly and is draped over one shoulder and hanging down his back. In the close up shot as he turns round, it is back on properly.
Continuity mistake: In the scene where Mr. Leaky is showing Bud and Doyle the t-shirt, Bud is sitting on the chair normal, but when the camera view changes to their backs, Bud is sitting on the chair backwards.
Continuity mistake: In the scene where Bud hits Doyle in the head with the encyclopedia, Doyle slams in to the shelves behind him consequently destroying them and knocking everything on to the floor. However, in the next scene, when Bud brings the girls in to see the injured Doyle, the shelves are whole again.