Corrected entry: In the sewer scene Reinhardt melodramatically puts his hand under one of the holes where sunlight is passing through and we see it starting to smoke. He is wearing gloves, why would his body react to the sunlight while it's covered?
Corrected entry: During the sewer scene, Whistler says "well some of us can't see in the dark, nipplehead". Fair enough, humans can't see in the dark, vampires can. So why do they have the lights on the guns? As a UV weapon, constantly on but filtered for quick access? That's just about OK. But that doesn't explain why Nyssa uses a flashlight in the house of pain as she searches the rooms/corridor/loft. (00:42:01)
Corrected entry: When Blade is fighting the masked Nyssa at his base of operations near the beginning of the film, towards the end of the fight, there are two shots that are created entirely with laughably bad CGI. The "characters" move WAY too fast, have unnatural "bendy" movements, and defy the laws of physics a few times, making them completely unbelievable. (The exceedingly low-quality of these shots is even joked about in the audio commentary). (00:22:00)
Corrected entry: Nyssa describes vampirism as an arbovirus where vampires are the vector. However the definition of an arbovirus is as an arthropod-bourne virus - arthropods are invertebrates with exoskeletons(insects). Not vampires.
Corrected entry: When a person is turned into a reaper, their lower jaw is supposed to drop out (as is obvious when they open their mouth 'proper' and feed on someone. Look at Nomak in his final fight scene with Blade. His lower set of teeth is quite visible, but they all disappear when his mouth opens.
Corrected entry: The heavily armed heroes walk around a nightclub. One even wields a drum-fed heavy machine gun - and no one in the club seem to notice or remotely care until people start shooting. Surely armed assault teams aren't that common a sight in these places?
Corrected entry: Towards the end Blade is strapped to a table and has spikes run through his wrists and thighs. Later he regenerates himself in blood and the wounds are healed. Fine, but there are numerous times after (the fight with Nomak, etc.) when you can see there are no holes in his pants from the spikes in his thighs. (01:27:44)
Corrected entry: In the House of Pain, when Nomak and Blade are fighting, Nomak runs away because a ray of sunlight hits him, but before that, when he gets shot in the head, he runs down some stairs full of sunlight. The sunlight on the stairs stopped Nyssa from running down them but how come it didn't effect Nomak seeing as that hall of stairs was full of sunlight when underground, there was only a little ray of sunlight.
Corrected entry: After Blade emerges from the blood fountain, he fights a lot of henchmen in hand-to-hand combat before taking on Reinhardt with his sword. When Whistler shoots the incubator after Blade kills Reinhardt, where are the bodies of the ones Blade fought hand-to-hand? None of them were vampires, so they wouldn't have disappeared. (01:37:42)
Other mistake: Towards the end of the film, after Snipes beats the crap out of a lot of vampires, Whistler throws Blade's sunglasses to him. They show him throw them in one shot, then in the next shot they show Snipes catching them. But look in the background at Whistler, he doesn't have the glasses, but is moving his arm like he is throwing them. The glasses must have been computer animated, and bad editing contributed to this mistake. (01:37:34)