Continuity mistake: At the end of the movie just after Johnny Depp makes his last run of drugs back, he is seated at a table with a curtain at his back. The curtain is split open and if you look close you can see someone standing behind the curtain - their hands are clasped together. Then as Johnny Depp goes to the bathroom and comes back the person is still there then he quickly walks away as Johnny Depp sits down.
Continuity mistake: In the scene where George is in California measuring the purity of the cocaine there is a topless woman with a blue bikini bottom in the background. The trouble is in the first shot she walks from right to left and sits down and then in the second shot she again walks from right to left and proceeds to sit in a different chair. This all happens within the span of a few seconds.
Add timeMichael Bailey
Continuity mistake: In the scene where George and Mirtha first meet at the party, there is a segment where they are talking. During the scene, Mirtha's hair goes from full (the Farrah Fawcett 70s style) to flat, back to full again, then flat, etc. Her hair changes back and forth between each frame change.
Continuity mistake: In the scene where Paul Reubens is smoking a joint and holding it with a roach clip, the length of the joint changes sizes throughout the scene. At one point it is almost completely gone, then the camera focuses on Reubens and the joint is only about half gone, then goes back to being almost completely gone in when the camera cuts back.