Other mistake: When Seth comes out of the pod for the second time and the girl is watching him she moves her leg reveling panties. However, Seth comes over and they start intercourse. How? He doesn't even move her underwear to one side.
Plot hole: In any given volume of air, there are any number of tiny, living organisms; dust mites, viruses, bacteria, etc. Why did the teleporter combine Seth's DNA only with the fly that was in the chamber? If he had taken the "floating organisms" into account in his calculations and programming, then why would he not have excluded ALL foreign DNA?
Seth Brundle: I was not pure. The teleporter insists on inner pure. I was not pure.
Ronnie: I don't know what you mean.
Seth Brundle: A fly... got into the... transmitter pod with me that first time, when I was alone. The computer... got confused - there weren't supposed to be two separate genetic patterns - and it decided to... uhh... splice us together. It mated us, me and the fly. We hadn't even been properly introduced.
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