Continuity mistake: The first time we see the young doctor doing his "lobotomy" in London Hospital (to the girl that was married to Prince Edward), Ian Holm comments on the procedure for some guest as they stand behind a glass window. You can clearly see the young doctor doing the third strike with his hammer in a reflection in the window. The movie cuts back to the young doctor and he is doing the third strike for a second time.
Continuity mistake: When Abberline draws the knife on the board its lines are jagged. When it cuts to different angles of the board the knife is completely different, smooth lines and it seems much larger and it is perfectly aligned on the board.
Continuity mistake: When Inspector Abberline is talking to his supervisor and requesting a qualified doctor, his bangs change from shot to shot.
Continuity mistake: When Gull shows Abberline his autopsy kit, Abberline takes out one of the knives and touches the middle of the blade with his hand. In the next shot, his hand has suddenly moved to the top of the knife and he's touching the point with a finger. In the following shot, his hand is on the middle of the blade again.
Continuity mistake: Immediately after Abberline arrives at the yard where Annie Chapman's body is found, there is a shot of a photographer taking a picture of the scene from a nearby building. This shows Abberline's coat and hat already hanging from the fence. The shot changes, and we are then shown Abberline actually hanging them on the fence. After this, the position of the hat and coat vary in different shots, sometimes being very close together, other times with a noticeable gap between them.