Continuity mistake: When Duke and Gonzo are driving towards Vegas in the beginning of the movie, they pull over to pick up the hitch hiker. Gonzo puts the car in reverse and goes backwards really fast, but Duke is being pushed backwards against his chair!
Factual error: At the second-to-the-last scene, where Duke sits in the chaos of the hotel room and reflects on the hippie and drug culture he is surrounded by, there are three television screens. One of those screens - the one right in front of him - shows a tank driving from right to left. This tank is recognizable as an M1 Abrams, which entered service not before 1980. (01:46:00)
Visible crew/equipment: During the beginning as the camera is moving all around the car, it comes along side. The reflection is visible on the front near the driver's side tire.
Visible crew/equipment: Depp walks into a room and trips over a woman. At the start of this scene, the camera is moving left to right. On the very left side of the screen near the corner is a piece of the camera. Its either part of the lens, or something attached to it.