Corrected entry: In this film it is revealed that the Minions were around long before joining with Gru but in the first Despicable Me it is implied that Gru created the Minions himself. In the girls' room a poster can be seen on the wall showing a schematic of the Minions during their final stage of design.
Corrected entry: It is revealed that the moon landing is fake and filmed by Stanley Kubrick in this movie, and we see an entire set built for it. Yet in the first Despicable Me, Gru is watching the moon landing on T.V. as a child, and the entire set we see is different than what we see in "Minions" including the different looking astronauts and the different camera positions.JaxxJaxx