Continuity mistake: 15 minutes into the movie, as the crew sits at a table to discuss frogs and the environment, there is a white bottle cap with a red dot on it in front of Carrie-Ann Moss. During the discussion the cap keeps changing right side up and upside down as the cameras change views.
Continuity mistake: At the ending climax as Bowman is cutting the oxygen pack from Gallagher, you can see Gallagher's name plate on the front. However as Gallagher was running we clearly saw him take off his own pack, toss it aside and put on Burchenal's. This is made blatantly obvious as the camera pans to the discarded pack on the ground with the name "GALLAGHER" printed on the front.