Character mistake: In Ch 14, Langdon muses on hatha yoga as an ancient Buddhist art. Yoga originated in the Rig Vedas, an ancient Sanskrit text, and predates Buddhism by around 2,000 years.
Factual error: In chapter 21 Vittoria states that "everything has an opposite. Protons have electrons." Protons and electrons are NOT opposites. The opposite of a proton is an antiproton, the opposite of an electron an antielectron (or positron). Other than having opposite charges, a proton is completely different from an electron, ie. a proton is a hadron made from 3 quarks, Up Up Down, making it a baryon. An electron is a first generation lepton and is a fundamental particle. As a physicist, Vittoria wouldn't make this mistake.