Trivia: The Avengers co-creator Stan Lee makes his usual cameo. This time as a man being interviewed by a news reporter asking about superheroes, at the end of the movie.
Trivia: Stan Lee makes a cameo appearance as a librarian at Parker's school wearing large headphones, unaware that Spider-Man and the Lizard are battling at the library behind him. (01:37:25)
Trivia: Kate Beckinsale's mother makes a cameo as a vampire in David's covenant. (00:33:20)
Trivia: The Pizza Planet truck, a fixture of nearly every full-length Pixar film, can be spotted in the Witch's Hut.
Trivia: In Shanghai, Bond spots the painting Woman with Fan, by Amedeo Modigliani. This painting was stolen in real life in 2010. This is similar to the first Bond film, Dr. No, when he comes across the stolen Duke of Wellington painting that had also been stolen in real life just before Dr. No began filming. Woman with Fan also shows up for a brief moment in Spectre.