Plot hole: When Andy turns into a werewolf, he kills both Amy and Detective Benbou. Later in the morgue, Amy tells him because of this that she is forced to become his "rotting sidekick." If this is completely true, then Detective Benbou should also be following Andy around but he isn't seen after Andy manages to escape from the morgue.
Plot hole: Dafoe and Bullock leave the ship a long time before it hits the tanker and there is a lot more time before it crashes into the town and even more before Alex gets on that speedboat. No matter how fast he could have gone, there is no way he would have caught up with them.
Plot hole: After Sid and her friend get out of the car, they run away from it. Yet somehow while they are talking, the killer climbs out of the car and ends up behind them without them seeing a thing.
Plot hole: The scene takes place in Julia Roberts' father's stable. Mel Gibson explains to Julia Roberts that he was supposed to kill her father, a judge, because he was going to reopen a certain case. Gibson says that he couldn't kill him and they became friends. He further explains that he was the one to talk her father into reopening the case in the first place. The problem is, they didn't meet until after he decided to reopen it, since that was why Gibson was supposed to kill him in the first place.
Plot hole: Katherine (Kirstie Alley) the tooth fairy is instructed by Rodgers (Lynn Redgrave) that she can only go out at night, otherwise she stays in an apartment in Limbo to get her assignments. She is given names all over the world. There is always a part of the world that is in nighttime. She should always be working and never at Limbo.
Plot hole: It makes no sense that Martin would be getting the invitation to the reunion mailed to his office (or to anywhere else.) He's had zero contact with the alumni committee, and they're not going to hire a private detective to find him. He also doesn't have contact with anyone else from his hometown who might have forwarded it; his father's dead, and his mother's not in her right mind. There's no explanation for why it would have ended up there except for needing to set the plot in motion.
Plot hole: In the waning seconds of the championship game, the Huskies are down by 2 and UMass has the ball. Not only do the Huskies not intentionally foul to stop the clock, but UMass attempts to run a play and set up a basket when they simply could have dribbled out the clock and won the game. Both these strategies go against what any basketball team would do in this situation, especially in a championship game.
Plot hole: Marcus told Melena he lived in New Mexico with his parents until he was 5 years old: "My dad died in a car accident when I was five... and my mom got caught smuggling people into the country, so she got 10 years [in prison]." Even though Marcus did not know at the time the real reason his mother was in prison, the murder must have occurred in New Mexico, so it doesn't make sense that she would be serving time in a New York prison. (00:33:20 - 00:34:21)