Continuity mistake: Before Eddie and Sam enter the Skobel building to retrieve the laptop, Viktor's red Mercedes is not outside. In the next cut scene it is automatically there.
Bug: In the Tomb of Tihocan level, water reflections can be seen on the walls even when the cistern is drained.
Other mistake: On the US PS2 Version, though the Sacred Cloths are spelled right on the inventory screen, when used, the letters are misspelled as "Scared Cloths". Other errors abound (such as grammar), but these are all due to the translation of the game from its native Japanese to English.
Plot hole: In the levels 'Rebirth 1' and 'Rebirth 2' Wesker encounters Lisa Trevor and during their fight he calls her Lisa Trevor. This makes no sense because in Wesker's report 2 he says he never knew her name. Quote from Wesker's Report 2: "Even now, I still do not know who she was and why she was brought here".
Continuity mistake: Link is left handed in all Zelda games thus far, except for the Wii version of Twilight Princess. He holds his sword in his left hand in this game, except when he is facing East.
Other mistake: When Jak is getting his new Dark Jak power in the Metal head section of the city (Dark Strike) there is a Metal Head behind him pouncing at some invisible wall. There is a invisible wall separating Jak and the rest of the game so the cutscene can go on uninterrupted.
Bug: When playing in the Malta Cup, if you end up playing Stephen Hendry, his head keeps rotating 360 degrees when you are on a break.
Bug: Although you can't light dynamite while underwater, the cigar that you light the dynamite with will still burn underwater.
Other mistake: In Havana, there is a secret car in an underground bunker, a mini. When you find and drive the car you can do a burnout, but the smoke comes from the rear wheels - no minis ever had rear wheel drive.
Other mistake: In a Roman temple the word artifact is spelled artEfact. And the Historical figure Hannibal Barca's name is spelled Hammilcar Barca.
Continuity mistake: In the last mission of the game, Sam is situated in an area where he has to sneak up on the big boss, and take him down along with his two men. Sam must do this very quietly as to not get seen or a timer will go off for 1 minute, and makes it that much harder to finish. You can hear the other characters making comments every so often, like "I think I hear something, or something down there is moving." And if Sam is not seen, you hear a character say "It's probably just the train." There is no train in this mission, there was one however 4 or 5 missions earlier.
Bug: When kicking a field goal or extra point, if the defense blocks the snap, the kicker will still go through the kicking motions and the ball will magically appear at his foot at the moment of impact and sail through the up-rights.
Continuity mistake: If your character faces left, whether left diagonally or straight left, the weapon(s) and/or shield in your character's hands is reversed from normal. This applies to all playable characters.
Continuity mistake: When Serge changes back from Lynx's body to his, he's naked is the room. However, when he goes through the doors, he's wearing his normal attire again even though no one gave him any clothes to put on.
Other mistake: During chapter 4, when chasing down the fat mob dude, you step in an elevator. Joe then takes a sip of a whisky bottle, however the bottle is capped.
Other mistake: At the end of level 1.8 (The Post Office: Break Out!) you will be in an office and jump out the window with people firing at you. However the windows only break from you going through it and not from any bullet fired in the same direction, which should have shattered the glass also.
Factual error: At the end of the game, go to Meteor Falls and search for Steven Stone there. Find him, and he'll want to fight with you. Before the fight, he'll remember that you battled along his side in the "Sootopolis Space Center." However, the Space Center is located in Mossdeep City, not Sootopolis.
Other mistake: Before the Madame Amberly boss fight, Cortex shouts at Amberly, "I'm an evil scientist!" just before Amberly is about to say, "A scientist are ye? To me you'll always be a little bug!" For some reason you can see a quick flash of her in a "T" pose.
Continuity mistake: If you go into the Hyperbolic Time Chamber and Buu comes in count how many people are in there. Three, but in "The Legicay of Goku II" Mr. Pope Says only TWO can go in.
Other mistake: The Prince's Sand Power Meter replenishes over time, no matter what the Prince is doing (Unless of course he is using Sand Powers to deplete it). However, after cutscenes, the Prince's Sand Power Meter is always empty.