Revealing mistake: After the opening credits there is a shot showing the house on the island where Karen and Stan live. If you look at the hanging chair, you can see that Karen is sitting in it. But in the very next shot she is in a meeting with Will, in a different outfit. This is a re-used shot from the previous season, which shouldn't be there.
Continuity mistake: When Grace is telling Will about his dad's affair, she mentions that he grabbed the other woman's ass when she brought him a packet of Goobers during the interval. The thing is, she sees them for the first time during the interval, and we see the conversation that follows. The mistress brings him wine, not Goobers, and he doesn't grab her ass.
Continuity mistake: When the guy at Will's party tells everyone the beer has gone, everybody leaves, and the guy puts his plastic cup on the handle sticking out from the keg. In the next shot the cup has suddenly gone, then reappears again in the next.