Plot hole: When Connie uses the wish machine to make Malloy small again, she instead wished for Ethel's breasts to get significantly bigger. However, in the next scene Ethel's breasts are back to her regular size. The plot shows that the wish doesn't wear off, and someone else would have needed to wish for Ethel's breast to get smaller but no one did.
Brickleberry (2012)
1 plot hole in season 3
Starring: Tom Kenny, David Herman, Daniel Tosh, Roger Black
Old Wounds - S3-E6
Continuity mistake: Steve brings Denzel a McRib sandwich and says don't ask how I got it. He shows Denzel his "purple" hand. When Steve takes the sandwich back, the purple color completely vanishes without him wiping it off.
Trivia: The scene showing Connie training to be a Navy Seal and being caught with a Thanksgiving dinner by Kirk comes from the scene in "Full Metal Jacket" where the drill sergeant finds a jelly donut in Pvt. Pyle's footlocker, including the line about eating it because they paid for it.