Question: Why does Lisle keep the potion's existence a secret? What's gonna happen if the public does know?
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Answer: As shown in the movie, the potion not only restores a person's youth and makes them immortal, but it would also stop the person from having any type of disease. If the public ever knew about it, everybody would suddenly start fighting to get it without realizing the damage it could do. Ex: At the end of the movie, Madeline and Helen both fall down the church steps and shatter upon hitting the ground. Better to keep it a secret from the whole world than let it get out and have people doing anything that could irreparably damage their bodies.