The One With The Ball - S5-E21
Corrected entry: While Sphynx cats are not generally hypoallergenic, Monica could not have had an allergic reaction because her exposure to the cat was minimal and she didn't touch it.
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Correction: Many people, like my mother, are highly allergic to a cat's dander or saliva and will have a reaction just being in a room where the cat had been. No actual contact is needed in order to have a reaction. The cat doesn't even need to be there at the same time as the allergic person. Monica could easily have still had an allergic reaction to the cat eve though her exposure was minimal and she didn't touch it.