The infamous politician (Ron Perlman) is the last guest that Cameron Diaz and the other roommates have dinner with. While they're discussing whether to kill him or not, he looks around the house and figures out that they're the ones responsible for the missing people and then slips some of the poisoned wine into their cups. The last scene is a painting of one figure with a blue bottle (the one with poisoned wine) and around him are five dead people with a voice over of the politician announcing that he's interested in running for president...
Plot hole: The group poison a dozen or so people and dispose of their bodies by burying them in their own garden. Some of their victims are notable celebrities - television presenters, authors, leaders of large and vocal pressure groups. Certainly some of them are nobodies, but nonetheless they are going to tell friends where they are going for dinner! Not one of these people told their assistants or their secretaries or a friend or a relative - a spouse? - where they were going and what they were doing on the night they were murdered? Not one of them? Not one single trace was left for the police to follow? Absolutely impossible.
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