Factual error: In the game at Pittsburgh, when Ruth hits three home runs, the first two were hit off Guy Bush. When he comes to bat the last time, Guy Bush is still pitching. This was not the case. Red Lucas was the pitcher, and he gave up Ruth's last home run.
Factual error: When the Babe calls his shot at Wrigley Field, you can see the ivy vines on the bleacher wall. The called home run shot was in the 1932 World Series, but the ivy wasn't planted until 1937.
Continuity mistake: There is a scene where Goodman is in the establishment where his future wife is working. There is a shot where it shows his beer glass with about 2 inches of head on it. The angle changes and in a matter of seconds, the head on the beer is gone.
Factual error: During the scene of the 1932 called shot pitcher Charlie Root is wearing jersey #11. He wore #12 in 1932.
Factual error: During the called home run against the Cubs at Wrigley field, the movie shows the home run flying over the fence and the basket on the outfield wall. The basket was not installed until 1970.
Other mistake: Early on, the Babe is seen showing up late at a game in Boston, staggering hung-over to the plate, and hitting a home run. But this was a home game; it would have been the bottom of the first, and if Ruth hadn't been there by game time, some other player would already be playing in his place.