Mutant Liberation Begins - S1-E2
Madelyne Pryor: [In labor pains] Logan, he's, he's here!
Wolverine: Who? Apocalypse?
Madelyne Pryor: The baby!
Wolverine: Oh, crap!
Remember It - S1-E5
Valerie Cooper: Most other nations don't allow a terrorist to be their leader.
Magneto: Yet so many allow their leaders to be terrorists.
Deliberate mistake: When the news program is discussing Gyrich's assassination attempt on Xavier from the series finale of the original animated series, he's shown to have his classic look of auburn hair and sunglasses. However, when this scene occurred, Gyrich had black hair and was not wearing sunglasses. This was done deliberately to match the character design of the original series prior to the final 6 episodes, when Saban took over and redesigned much of the show's look.
Trivia: Ross Marquand, who voices Professor X, previously portrayed Red Skull in Avengers: Infinity War and Avengers: Endgame. Cedric Smith, who voiced Professor X in the original animated series, also voiced Red Skull in one of the series' final episodes. Marquand has described voicing the same two characters as Smith as kismet.