KeyZOid

Answer: From what I could see, it was never specified what caused their strained relationship. Many sisters just don't get along for a variety of reasons-jealousy, resentment, rivalry, personality clashes, etc. Of course, it serves the plot and is a common movie trope that Cecilia has little family support to help with her situation, adding to the suspense as she tries to escape Adrian on her own.

raywest

Answer: Controlling husbands like Adrian severely restrict who their wives can see and talk to, so Adrian most likely interfered with Cecilia maintaining a positive relationship with her sister. Cecilia's sister probably did not know how controlling and manipulative Adrian was, so assumed it was Cecilia who did not want to be close to her. Adrian made it appear as though it was Cecilia's choice, but it was actually the restrictions he placed on Cecilia that caused the strain between the sisters.

KeyZOid

Answer: Because an email was sent from Cecilia but really from Adrian (the invisible man) saying that her sister was suffocating her. And that Cecilia didn't want to see her anymore.

And these were the types of stunts Adrian had been doing for years, creating tension and causing spite between the sisters.

KeyZOid

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