Corrected entry: When Dr. Doom is trying to eliminate the Fantastic Four, he makes Ben 'normal', then he freezes Reed, incapacitating him, and then he believes he destroys Johnny with the missile. He then says, "Two down, two to go". He should have said, "Three down, one to go". He thought he had taken Reed, Ben and Johnny out of the picture and he had no way to know that Ben had regained his powers.
wizard_of_gore
20th Jan 2009
Correction: He took Ben's powers away and thought he had killed Johnny. That's two down. He was still in the process of taking out Reed but hadn't completely done so yet, so it wasn't three.