Continuity mistake: Mention is made that Pamela owns the brewery because she has just turned 21. During the scene with the video game, she says her birthday was October 21, 1959. Later, the lawyer for Bob and Doug establishes the movie's timeframe by mentioning her kidnapping on October 10, 1983, which would make Pamela almost 24 years old instead.
Continuity mistake: The brother, disguised as a doctor, enters the hospital and kills a patient by injecting him with some kind of poison. The problem is that the huge hypodermic needle stays at the same fluid level before and after the injection and afterwards has a quarter inch of air in it.