Revealing mistake: As one of the lab crew is showing Tomas Jane the suspended tiger shark you can see a horizontal line in the water in the background. this is the edge of the water tank used to film the exterior scenes (mentioned in DVD extras).
Russell Franklin: Just what the hell did you do to those sharks?
Dr. Susan McCallister: Their brains weren't large enough to harvest sufficient amounts of the protein complex. So we violated the Harvard Compact. Jim and I used gene therapies to increase their brain mass, a larger brain means more protein. As a side effect the sharks got smarter.
Janice Higgins: You stupid bitch!
Trivia: In both Jaws and Deep Blue Sea there is a scene involving a license plate. In Jaws it is removed from the belly of the dead tiger shark. In Deep Blue Sea it is removed from the teeth of a tiger shark. Not only are both sharks the same but both plates are from Louisiana. The license plate number is the same in both films: 007 o 981 Exp 72-73.
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