Trivia: All of the scenes in this movie were shot in only one take and in one scene the technique really shows. When Jimmy Stewart is drunk, he ad-libbed hiccuping while he was talking. Cary Grant, not expecting the comic relief, had to look down at the floor to keep from laughing (you can see him grinning and collecting himself).
Trivia: Hepburn wanted Clarke Gable and Spencer Tracy for the male roles, but the studio gave her Cary Grant and Jimmy Stewart instead. (She did get Spencer eventually when requested for Woman of the Year).
Trivia: Katharine Hepburn played this role on broadway, it was written for her. She had Howard Hughes buy her the movie rights so only she could play it at the movies. She didn't want any other actress playing Tracey Lord.