Plot hole: Antoinette Lilly makes headlines as being murdered and her husband is charged and sent to a criminal asylum...despite the fact that no body has been found and no one has even bothered to go to the hotel or town she was last at to investigate whether or not she's alive or dead. Not believable.
Suggested correction: John was framed by Antoinette's step-mother (who stood to gain Antoinette's inheritance). People have been arrested for murder without a body being discovered first though. Additionally, we find out that the lawyer who helped framed John also paid him to confess to the crime and admitted to being mentally unstable. So nobody was even trying to look for Antoinette.