Character mistake: Towards the end of the movie when the Giganotosaurus is attacking the group and Claire gets the rope wrapped around her leg and pulled towards the dinosaur Owen actually shouts Bryce before saving her instead of Claire.
Factual error: As the C-119 cargo plane is going down over the Bio-Syn reservoir, the right wing snaps off, separating completely from the aircraft. As a result of upward lift forces pushing upward on the left wing no longer being countered by an equal lift force from the right wing, the aircraft would roll very quickly to the right. However, after the right wing separates, and just before the scene cuts away, the C-119 dips to the left.
Factual error: The deer in the forest somehow does not hear the giant dinosaur approaching, so doesn't run away. (01:21:10)
Continuity mistake: Towards the end of the movie, Malcolm, Grant, Ellie, and Maisie are in a Jeep that tumbles down a hill. As it is tumbling, an impact extinguishes the headlights and interior lights. However, as the Jeep comes to rest at the bottom of the hill, the lights are back on. They remain on for all the following scenes. (01:44:53)

Continuity mistake: When Masie walks into her room and slams the door, making some items fall off the shelf, the remaining items differ when Claire goes to open the door a few seconds later. (00:27:20)
Continuity mistake: When the Atrociraptors are released, one of the cages is sideways, but in the next shot it's the right way up.
Continuity mistake: In the scenes where Ellie and Grant are flying to the Biosyn facility via helicopter - all the interior shots show them flying over a solid layer of clouds. However, in all the exterior shots of their flight, there is a not a cloud in sight.
Revealing mistake: When Charlotte Lockwood is doing a vlog holding baby Maisie, the needle she uses pokes Maisie's leg twice, which couldn't happen in real life.
Revealing mistake: While in the helicopter, Alan's eyes do not align with the location of the Dreadnoughtus. Alan is looking to his far right before the helicopter even approaches the dinosaur and it is shown across the front of the screen. Alan's eyes then stay fixed straight ahead (even after passing the dinosaur), giving the impression he's looking at the dinosaur, but he would have needed to keep turning his neck to the right as the helicopter flew past in order to keep it in sight. (00:35:14)
Suggested correction: It's a common movie trope. The two things aren't happening in sequential order. They're happening at the same time. Alan isn't looking before the helicopter approaches the dinosaur...you're seeing the inside of the helicopter as it approaches and passes the dinosaur. They're happening at the same time.
Continuity mistake: After Claire dives into the lake to avoid the dinosaur from spotting her, when she sticks her head out, her hairstyle changes between shots. (01:21:54)

Revealing mistake: When the truck stealing Blue's baby drives off just as Owen spots it, dirt tracks are visible in the fresh snow from previous takes. (00:28:10)

Continuity mistake: When Ellie is talking to the farm owner, her position in relation to the tractor changes from the closeup to the long shot. She ends up further away. (00:19:10)

Continuity mistake: When Ellie is caressing the baby dinosaur, she has both hands on it's face. When the shot changes one hand is now on the concrete barrier. (00:25:00)
Other mistake: Maisie rides her bike down the snow-covered hill, but when she stops in front of the cabin there is no snow in or on the tire treads and the tires look dry. (00:12:23)
Continuity mistake: During the Jeep's roll-over down the hill, at least the front passenger tire was bent outward/damaged. (It looked like two tires flew off, but all four tires were still on when the Jeep landed on its roof.) The positions of the four tires varied a few times afterwards, from being straight to turned to the left to turned to the right and the tire that was bent outward appeared to be intact (not damaged). (01:44:52 - 01:47:32)
Revealing mistake: Before the Jeep roll-over, the four people inside were looking upward through some type of 2"x2" fencing (?) as the roof to see the bugs on fire in the sky. The Jeep had a luggage rack and luggage on top, so the "fence" as part of the roof did not make any sense (other than for filming purposes). (01:43:55)
Continuity mistake: Alan had a large brown shoulder bag before he went into the building to listen to Ian's speech, but (like Ellie) did not have his shoulder bag when he got into the lecture hall or after exiting the building. (00:37:20 - 00:40:13)
Continuity mistake: Before Ellie went into the building to hear Ian's presentation, she was wearing a royal blue sleeveless coat over a brown long-sleeved blouse and had a large brown shoulder bag/purse. When Ellie entered the auditorium, as well as when she went outside after the presentation, she was not wearing the blue coat plus she now had a wallet-sized hand purse but no large shoulder purse. Even IF there was a coat check-in, Ellie would not have left her shoulder purse/bag behind. (00:37:06 - 00:40:13)
Continuity mistake: When Owen and Claire were sitting at the outside table talking to Franklin, the amount of water in their glasses changed a few times (but neither drank any). Side-rear views of Owen's glass tended to show it about half full, but front views varied from quite low to about two-thirds full. Front views also showed discrepancies in the amounts of water in Owen's and Claire's glasses, such as both about half-full but later Owen's glass two-thirds full and Claire's less than half full. (00:32:00 - 00:33:05)
Continuity mistake: In Malta, when Owen is told that Maisie is being sent to the lab, his hand is raised next to his ear. A shot later, it's lowered.