Plot hole: The movie is based in 1986 after the group time travels from 2010. That makes it a 24 year trip back in time. It is stated that Jacob is 20 years old. That is an error as this would make him roughly around 23 or 24 if he was conceived in 1986, which we saw near the end of the movie.
Suggested correction: This mistake has already been corrected. Cusack could have simply generalized his age when he mentioned it, probably not remembering his real age at the moment.
Plot hole: If the cars are assigned on a "first come, first served"-bases, how can the tv programme have footage of the drivers posing with their cars, seeing as not all of them survive?
Plot hole: The water-borne biological weapon makes every individual a crazy murderer, right? Near the beginning a man burns his house with his wife and child inside. So then why do the three hunters not try to kill each other or the crazy wife in the nursery not try to kill her son?