Continuity mistake: When they find out Lecter is on the elevator, they look down the shaft at him and there is quite a lot of blood on his back, so much that it even reaches down to his belt. However when they open the elevator shaft and the body falls down, there is only a small amount of blood on his back. (01:23:40 - 01:24:50)
Continuity mistake: When Sam is talking to the P.I about "Taking care of Max," he gets into his car and the window is up. A few seconds later, the window is down. There wasn't enough time for him to roll it down. (00:54:50)
Revealing mistake: When Ricky is shot through the chest, the blood pack is visible bulging through his shirt. (01:28:30)
Other mistake: Just after the assistant warden has been carried away by the other inmate, it cuts to the warden in the kitchen with his son and a guard. When the guard tells him the menu for tomorrow is ready, the subtitles "Sir, the prisoner's menu for tomorrow is ready." The apostrophe in "prisoner's" is shown in the wrong place. Saying "prisoner's" implies that it's just for one prisoner, and since the menu is made for all of the prisoners, the subtitles should have read "the prisoners' menu" and not "the prisoner's menu." The guard even says "They'll have some beans, vegetables and meat for lunch" afterwards, so multiple people were being referred to. (This depends on which format and which studio distribution you are watching, but it can definitely be seen on the Region B Blu-Ray distributed by MediumRare). (01:21:15)
Character mistake: Whoever wrote the "homicide" memo on the captain's corkboard spelled "homicide" wrong.
Continuity mistake: Towards the end of the movie, when the mob appraiser has verified the medallions are authentic, he is wearing two white gloves. He then asks if he can leave. When he stands up and gathers his things, he has only one glove on. The shot cuts away. When it cuts back to him, he has two gloves on again. (01:32:50)
Continuity mistake: When Proctor shows Campanella the traumatized patient, he is holding a Spanish dictionary on one hand. In the next shot, he's holding it with both hands.
Revealing mistake: When Angelo is shot in the back at the airport, you can see a pack underneath his shirt when he is rolled over by Utah. (01:39:44)