Other mistake: When in Oscorp, Peter and Gwen are walking along with Alistair Smythe and some other scientists while transporting what appears to be Scorpion in a pod. The black scientist is wearing glasses that the frames are very reflective of light, and when Alistair is saying, "I don't have time for this," the black guy looks at Gwen, and there is bright light reflecting off them. Then the lighting texture suddenly changes and shifts, with there being less light in an instant.
Revealing mistake: After saving a civilian, sometimes they will pull out a cellphone to take a picture of Spider-Man. If he is standing too close, the character model has the civilian putting the phone through Spider-Man's chest.
Revealing mistake: Some of the NPCs driving around, like the women, have character models that are slightly too small. Their hands don't line up on the steering wheels in the vehicles and are holding the air behind them.
