Trivia: The man working on the burger van is reading a copy of The Da Vinci Code - interesting as the book is about the Jesus blood line.
Trivia: Maya Rudolph, who plays the pregnant character Molly, was actually pregnant during the filming of the movie.
Trivia: Actress Amy Adams makes a small cameo during the "Master Exploder" sequence. She is the woman who mouths "I love you!" to Jack Black, and is subsequently covered with the brains of the man whose head explodes.