Question: In one of the first episodes, Brian sees a miniature horse-drawn wagon come around the couch and he chases it into the kitchen, where it disappears into the wall. What is this a joke about or reference to?
Answer: Chuck Wagon dog food commercials - the Chuck Wagon would ride through the house with the dog chasing it only to disappear into the kitchen cabinet where the box of dogfood was kept.
Question: In the courtroom, after everyone goes "Oh no.", what looks like a teapot bursts through the wall going "Oh yeah.". I'm assuming it's a US advert, but I've got no idea for what - can someone let me know?
Answer: It's the Kool Aid mascot (Kool Aid being a fruit flavoured powdered drink mix - FILLED with sugar). It has been bursting walls (while screaming "Oh, yeah!") for years, bringing what's needed to quench children's thirst.
Question: In this episode Meg pretends to be a lesbian, when she calls herself a 'mega lesbian' it shows four other 'mega lesbians' singing something on deep voices. What song are they singing? Is it a real song?
Answer: It's a real song called "Elvira". Originally by Dallas Fraizer in '66, however, this version seems to be the Oak Ridge Boys cover version. However, the mega lesbians skip the verse and just sing the chorus after the opening line.
Question: Last line of the show, Stewie says "can I interest you guys in two and a quarter way". What does that mean?
Answer: He's insisting that he joins in on Peter and Lois having sex. Usually sex between three people would be called a "three way", but since Stewie is only a baby and hasn't fully grown up yet, he would only be a quarter of a person, which would equal up to two and a quarter people.
Question: In the beginning of the episode Lois says Meg looks like Rachel something in a condescending way. Was there another joke there?
Answer: The "Rachel something" Lois was referring to was Rachel Maddow. Also, Lois never said Meg looked like Rachel Maddow, she said Bonnie said she was pretty and Meg asked how it came up and Lois replied "Oh! You know, we were talking about pretty people, and I said Rachel Maddow and she kind of took the baton from there and said Meg Griffin". The joke here is that later in this scene, Meg asked who Rachel Maddow was and Lois replied "A model", however, Rachel Maddow isn't actually a model, she's a presenter, political commentator and author. Lois was just trying to get Meg to take care of Joe and Susie for the week.
Question: Why do Chris and Meg wear their hats 24/7?
Answer: In season 11 episode 7 "Friends without Benefits", it was revealed Meg's heart was literally born in the wrong place and ended up in her head and her heart beats were shown beating on her head. Meg just wears the hat to cover it up. As for Chris, it's pretty much just a simple character decision. The real explanation is most likely that's it's a lot easier to animate characters with a near-permanent appearance.
Question: Is it just me, or does the way Stewie says "Laugh and cry" in the opening titles change in different episodes? In some episodes it sounds like he's saying something like "Leff en cry" but in other episodes it sounds like "Laugh and cry".
Answer: In the first two seasons, the words "... Laugh and cry" sound to many like "effing cry" (or, "f-ing cry"). Aware of this confusion, Seth McFarlane re-recorded the line for the third season, enunciating more and emphasising the hard "L" sound in the word. From the fourth season, when the show was revived, it reverted to the original way.
Question: At the trial, Carter's lawyer asks Brian the star of two films he rented - Brian replies "Pauly Shore" and everyone seems shocked. Is there supposed to be a joke behind this? If so, what does this joke mean?
Answer: They were shocked that anyone would rent movies starring him - he is a bad actor.
Question: In this episode, Peter and Brian escape the rehab centre to visit the teenage pregnancy clinic, where they prank the girls who are asleep by dipping their hand in a dish of water, which causes them to give birth prematurely. How does that prank make that happen?
Answer: It's a common slumber party trick to put someone's hand in warm water, which is supposed to relax the person and make them wet the bed. Peter and Brian's plan just worked better than they'd planned.
Question: In the alternate timeline, Quagmire and Lois are married. In the kitchen, Lois takes a pie out of the oven and Quagmire says "Hey honey I'm ready for your pie and you made dessert too". Now I know this is some sort of sex joke or dirty pun. But what exactly does the joke mean?
Answer: Pie is a slang for a woman's vagina. That's the meaning of this double entendre. He want to have sex with her and she just happened to have baked dessert.
Question: Does any character in the show beside Brian and other kids his age understand what Stewie is saying? Or is it that Stewie doesn't realize it?
Answer: It's been brought up on the show itself that Brian and the immediate family understand Stewie. After that, others can understand him whenever it's convenient or needed for the story.
Question: When Brian tells Stewie, "It might be the "C" word." and Stewie asks "What the hell does that have to do with anything?" What is Stewie referring to?
Answer: Stewie thinks Brian is referring to the word "c**t", which is a vulgar slang term for a woman's vagina.
Question: When Brian went to see his ex, Tracy Flannagn, and Tracy announces Brian has a son, why does Stewie start chanting, "Jerry! Jerry!"? Is that a reference to something or what?
Answer: It references "The Jerry Springer Show" a "trash TV" talk show where people are often confronted with unknown children, their partners' secret lovers, etc. The crowd often chants the host's first name during the show.
Question: I've noticed in the last two seasons that certain jokes and gags are ruined because the characters explain the whole point of them. Why do the writers feel that their humour needs to be explained?
Answer: It's a meta joke. The "explaining the joke" is itself a joke, usually about how the family guy writers themselves recognise their reliance on certain types of humour.