Continuity mistake: When young Picard sees his "father" Riker, he says to turn on the computer in schoolroom 8. In the scene showing the children gaining access to the computer, the terminal they are at shows classroom 7 across the header of the screen. (00:36:20 - 00:39:55)
Revealing mistake: In the corridor, as Wesley faces the Zaldan, the hallway behind the scene is obviously a painting due to the shadow of the support on the edges.
Visible crew/equipment: As La Forge and Crusher leave the bridge, and the camera closes in on Riker, there's a shadow of a piece of filming equipment on the wall behind and to the left of his head, at the upper right of the shot.
Plot hole: The entire premise of the episode is contradictory; the franchise makes abundantly clear through the so called Prime Directive that the Federation abides to a code (often creating moral dilemmas that may require to stretch the rules) that says that their staff is not supposed to interfere in world that haven't reached warp capabilities, nor involve themselves in their internal matters. In the first half of the episode, Riker and the others just go 'mingle' with the frisky natives without a care in the world, and yet in the second half the Prime Directive itself is referenced explicitly and it is part of the plot.
Suggested correction: They are just enjoying the hospitality of the planet's inhabitants. They are not interfering in their internal affairs or the development of their species. It's only when Wesley gets into trouble that the Prime Directive comes into play. The entire mission of The Enterprise is to make contact with other planets.
Even though they are supposed to make contact with other planets, it's pretty clear in the rest of the series after the first few episodes of Season 1 that they do not (intentionally) contact people that have no warp capability.
Plot hole: The binars needed two people to upload the data back to their world but they only intended on keeping Riker in the holodeck. Riker is just one person. Picard came into the holodeck purely by accident - even Minuet said this was true. If Picard hadn't been there, Riker could not have uploaded the data on his own and the binars' plan would have failed.
Suggested correction: The Binars only trapped Riker because they thought they might need someone to restore the computer for them, which wouldn't have taken 2 Enterprise crew members. It was the fact that the Binars got to their planet too late that required Picard and Riker to work together. However, the Binars already knew Picard was on the Holodeck before they initiated their plan because when Picard exits his ready room he says he's going to join Riker. Had Picard not done this, certainly the Binars could have kept a 2nd crew member on-board somehow, if needed.
Conspiracy - S1-E25
Revealing mistake: After the fight with Riker, Quinn throws Worf through the room, hitting a wall. The replicator part of the wall moves.
Visible crew/equipment: Numerous times in the bridge scenes, the studio lighting rigs are seen in reflections on the work station screens.
Other mistake: After the report that Picard is close to death, the scene shifts to a close up of La Forge's hand turning on controls. If you look closely, you can see that both panels are re-purposed CANX-23429 remote control units. The markings are for volume, radio, transmitter, receiver, phone jacks and a microphone jack.
The Pegasus - S7-E12
Continuity mistake: In the opening log entry of the first episode, Picard says that "I have been informed that a highly experienced man, one Commander William Riker..." He sounds as though he has been assigned a First Officer without knowing him. However, in this episode he tells Pressman that he read Riker's file, and wanted him, based on Riker's adamant refusal to obey an order that went against his safety protocol.
Suggested correction: There's no error here. Picard likely read the files of many officers and requested the ones he preferred, and Star Fleet informed him which one he would get.
Revealing mistake: In an overhead shot of the Brattain, it's clear that the ship's (misspelled) name is just a poorly applied decal.
Visible crew/equipment: While Picard talks to Rasmussen in his ready room, when Rasmussen says, "I can't get quite as worked up as you," it cuts to a wide shot, and there's a white tape mark (T-mark) taped to the floor under the desk. (00:32:45)
Visible crew/equipment: On Romulus, when Picard and Data are told, "Eat your soup, courtesy of a loyal establishment," the camera turns to face the duo dressed as Romulans, and an actor's T-mark is visible on the ground behind Data. (00:42:40)
Visible crew/equipment: Boom action is visible in reflections on computer consoles in the back, while Picard and LaForge talk to each other on the bridge. (00:40:15 - 00:40:46)
Continuity mistake: When Data goes into his laughing fit, Troi is at her regular seat, but when he stops and remarks it was a wonderful feeling, the wide shot of the crew shows her seat empty. But then, when Picard is hailed, when the moon returns to its orbit, Troi is back at her seat.
Continuity mistake: When Lore backhands Worf in the turbolift, his eyes close but open back up as he is sinking down. Then, in the close-up, his eyes are closed again.
Visible crew/equipment: After the intro, when Garvin tells Gia to go home, Data is standing on the stairs and the actor's green mark is somewhat visible at Data's feet. This green T-mark is clearer when Data hands Garvin the radioactive box he's carrying. Then, when Garvin walks over to the table, there's an orange T-mark on the ground. (00:04:55 - 00:07:40)
Visible crew/equipment: After Gia tells Data to remove his hood, he asks how long it will be until Skoran and the others return. Then, when Data tells her that he must hurry he takes a step forward, and a green tape mark is visible on the floor. (00:36:35)
Visible crew/equipment: While Troi tells Riker about the Captain's grueling negotiations between the Gemarians and Dachlyds, when Picard joins them on the bridge, there are three visible T-marks taped to the floor. (00:01:50)
Other mistake: During his final discussion with Tomalok, Picard tells him that the Enterprise will escort the Romulan ship back to The Neutral Zone. However, as the episode ends, the two ships are heading off in opposite directions. Both the Enterprise and Romulan warbirds have demonstrated in the past that they can spin on their axis from a standstill. There is no reason for either ship to head away from the other to turn around.