Quotes
Peter Parker: A hundred bucks? The ad said three thousand.
Wrestling Promoter: Well, check it again, web head. The ad said three grand, for three minutes, and you pinned him in two. For that I give you a hundred, and you're lucky to get that.
Peter Parker: I need that money.
Wrestling Promoter: I missed the part where that's my problem.
Mistakes
Why would Columbia University have the "most powerful electron microscope on the eastern seaboard" in the same lab room as it would have the spider lab, which is a biology/genetics study? Electron microscopes are useless for studying DNA. The electron beam turns molecules into sludge. All but the toughest organic samples have to be coated with metal as protection, and you can't do this with DNA. See more...
Trivia
The scientist assisting Norman Osborne, who he then kills, is named as Dr Mendell Stromm, the same as a character who became The Robot-Master in the comics and was an enemy of Norman before we found out he was the Green Goblin. See more...
Movie Mistakes blog
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Other great sites
When Mary Jane is being mugged by four men, Spider-Man throws two of the men into two windows behind Mary Jane. The shot switches to Spider-Man beating up the other two guys. When it cuts back to Mary Jane the two windows are intact.
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