When Osborn is laid on the stretcher about to enter the vault, the cables by his right shoulder change positions between shots. See more...
Tobey Maguire's (Peter Parker/Spider-Man) brother is in the cable car during the bridge scene along with the other extras. See more...
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Uncle Ben: Remember, with great power comes great responsibility.
Bonesaw McGraw: What're ya doin' up there?
Spider-Man: Staying away from you. That's a cute outfit. Did your husband give it to you?
J. Jonah Jameson: He doesn't want to be famous? Then I'll make him INfamous!
Uncle Ben: Peter, look. You're changing. I know. I went through exactly the same thing at your age.
Peter Parker: No. Not exactly.
Green Goblin: You've spun your last web, Spider-Man.
Mary Jane: He's saved my life twice and I've never even seen his face.
Peter Parker: A hundred bucks? The ad said three thousand.
Wrestling Promoter: Well, check it again, web head. The ad said three grand, for three minutes, and you pinned him in two. For that I give you a hundred, and you're lucky to get that.
Peter Parker: I need that money.
Wrestling Promoter: I missed the part where that's my problem.
Peter Parker: Not everyone is meant to make a difference. But for me, the choice to lead an ordinary life is no longer an option.
Mary Jane: Who are you?
Spider-Man: You know who I am.
Mary Jane: I do?
Spider-Man: Your friendly neighborhood Spider-Man.
J. Jonah Jameson: If we can get a picture of Julia Roberts in a thong, we can certainly get a picture of this weirdo.
Peter Parker: You don't trust anyone, that's your problem.
J. Jonah Jameson: I trust my barber.
Aunt May: You do too much - college, a job, all this time with me... You're not Superman, you know.