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Factual error: This is both a misspelling in the subtitles and a factual error: During the tricycle race at the homecoming competition, Arnold Poindexter gives Toshiro Takashi a pill and tells him, "This is trichloromethaline, it counters all effects of alcohol in your system". It's spelled "trichloromethylene" which is another term for chloroform. http://msgboard.snopes.com/message/ultimatebb.php?/ubb/get_topic/f/39/t/000989.html.
Continuity: When Gilbert is handed the mic to talk at the pep rally at the end, his left shoulder is covered with grass and dirt from being thrown on the ground. However when the camera shot shows him first talking to the crowd, all the dirt and grass is significantly less and even completely disappears once Betty and the rest of the nerds come up to join them.