Sheldon: Pleased to meet you, Dr. Gablehauser. How fortunate is it that the university has chosen to hire you, despite the fact that you've done no original research in 25 years and instead have written a series of popular books that reduce the great concept of science to a series of anecdotes, each one dumbed down to accommodate the duration of the average bowel movement. Mahalo.
Leonard has his phone on his left ear. Sheldon says "Since ears don't cross hemispheres..." This is an error. The vast majority of the input to the left (or right) ear crosses over to the opposite hemisphere. See more...
Sheldon's laptop has gone through several strange transformations throughout the series, but in this episode it takes the biscuit - it appears to be a Dell XPS with the back covered up, but the shot of Sheldon chatting only to Amy shows that it's apparently running MacOS X. See more...
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The Big Bang Theory (2007) - 30 with pictures
Screenshots of mistakes that have been online for less than a year are only visible to members, but the rest are available to everyone. Don't forget to check out the picture of the day, updated daily, and the top 30 screenshots too.
Updates: Series 2
Continuity: When Raj's parents tell him to put his laptop down and gather his friends, they all huddle around the one-seat sofa. Sheldon is crouched to the left of the seat with his hands on the sidearm, yet in shots angled at the left he has disappeared from his place (as to not obstruct these particular angled shots.)