The Habitation Configuration - S6-E7
Continuity mistake: When Howard is almost done moving out of his mother's house, there is a table in front of him with a measuring device in the top corner. In one shot, the device moves to the opposite corner of the table. In a few shots later, the item returns to its original position.
The Barbarian Sublimation - S2-E3
Revealing mistake: When Sheldon gets the sword for Penny in the game, Penny walks out and you can see the laptop isn't switched on. (00:07:55)
The Fuzzy Boots Corollary - S1-E3
Continuity mistake: When Sheldon is telling Leonard that he didn't ask Penny out, there is a yellow food-bag on the counter between them that keeps changing its position with every shot change. (00:11:15)
The Hamburger Postulate - S1-E5
Continuity mistake: At the end when Sheldon has got a burger, the amount of burger left changes depending on the camera angle. Most noticeable when he asks Penny about permanently reserving the table - between shots the lettuce disappears, the bun changes colour, and the bite marks change.
The Hawking Excitation - S5-E21
Character mistake: The sign on Howard's laboratory door reads "RESTICTED area".
Continuity mistake: In the laundry room when Penny is talking to Sheldon, Sheldon takes some time arranging a blue shirt on his plastic laundry folder. Then it suddenly turns into a pair of socks, which he folds and then picks up the blue shirt again. There was not enough time for him to switch out the shirt for the socks. (00:06:30)
The Cruciferous Vegetable Amplification - S4-E2
Character mistake: In the first scene, on Sheldon's board are the words "D-D Fushion." This should be fusion. Sheldon wouldn't make a mistake like that.
Continuity mistake: Penny throws a black iPod out the window, but when Raj comes in having found it on the ground outside he has a silver one. (00:01:00 - 00:02:45)
The Vartabedian Conundrum - S2-E10
Continuity mistake: When Leonard and Penny are talking in the dryer room, the size of the towel Penny is folding keeps changing. (00:15:00)
The Big Bran Hypothesis - S1-E2
Continuity mistake: At the end of the episode, when the gang is reading the furniture assembly instructions, a pencil in the cup in front of them suddenly vanishes. (00:19:00)
The Creepy Candy Coating Corollary - S3-E5
Continuity mistake: At the dinner, Howard's mom calls. Howard's wine glass refills itself between shots. (00:15:20)
The Robotic Manipulation - S4-E1
Continuity mistake: In the ER, the glasses around the nurse's neck move instantly without her touching them. They go from angled to straight instantly. (00:17:45)
The Fuzzy Boots Corollary - S1-E3
Continuity mistake: When Sheldon, Howard and Raj play Jenga, there is one block sitting at the top of the tower. When Leonard walks in, there are now two blocks at the top, before we actually see Howard place the second one on the top. (00:08:10)
The Luminous Fish Effect - S1-E4
Continuity mistake: When Leonard and Sheldon are walking downstairs, Sheldon stops and pins back up the caution tape that is in front of the elevator. Between shots, the other strip of caution tape untwists itself. (00:01:25)
The Higgs Boson Observation - S6-E3
Continuity mistake: At the end, when Alex and Sheldon are at the apartment, when Alex says "she seems nice", there are two beer bottles on the coffee table. The camera goes to Sheldon, and when it returns to Alex, there is only one bottle.
Suggested correction: Genes can be dormant. Which allows them to skip generations. Therefor Missy's children could actually get the "mutated" gene. This is especially true since Sheldon and Missy are twins. Also, since the episode is about who out of Leonard, Howard or Raj, Sheldon would allow to "mate" with his sister, there is the added "insurance" of getting any smart genes from any of the 3 Lothario's mentioned above.
If you are going to try to argue with a geneticist about genetics, please use the correct terms. Sheldon is not referring to a recessive gene - there is no such thing as a dormant gene - he is speaking of a randomly mutated gene. Those are the words he used. If he had inherited a homozygous recessive karotype - one recessive gene from each of his parents - then somewhere in his family tree there would similarly gifted people, in which case he would use the correct term - a recessive gene. If Missy is a heterozygotic dominant karotype possessing the recessive gene for super-genius and the dominant for ordinary intelligence then mating her with Howard, Raj or Leonard would be a waste of time as their dominant genius gene would prevent the recessive super-genius gene from being expressed in the phenotype of the resulting child. The child would be highly intelligent but not on Sheldon's standards. It doesn't matter if Sheldon does not know any of this as he refers several times to a randomly mutated gene, not a recessive one. Missy does not carry the super-genius gene. The posting is correct.
Sheldon is prone to magical thinking when necessary to preserve his obsessive need to control his environment. He may have simply ignored the flaw in his reasoning, as even the most intelligent humans do when venturing outside their ares of expertise. He may be interested in the science of genetics, but his Ph.D. in physics doesn't qualify him as an expert in that field.