Series 
Continuity: In "Bubblestand" after Squidward blows the huge bubble, he tells Spongebob and Patrick that the ability to blow bubbles is in his genes. If you look at the position of the bubblestand sign, the sign is facing the direction Squidward is talking. The sign had always been facing the street, which means that Squidward was actually talking towards the street, when Spongebob and Patrick are actually to his right.
Great sites
Quotes
[Squidward believes Spongebob has swallowed an exploding pie.]
Squidward Tentacles: We gotta call the hospital!
Mr. Krabs: Won't do any good. I've seen this before. When that pie hits his lower intestine - boom!
Squidward Tentacles: You've seen this before?
Mr. Krabs: 11 times, as a matter of fact.
[Squidward calls the hospital anyway.]
Squidward Tentacles: Hello, doctor. Won't do any good? 11 times?!?
Trivia
Tom Kenny, the voice of Spongebob, had other minor roles in Spongebob. He is the police officer in F.U.N., Patchy the Pirate, Gary, the man from "Hooky" ("He burnt my shake"), and many others. See more...
Movie Mistakes blog
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Bubblestand / Ripped Pants (season 1, episode 1)
Continuity: When Spongebob first shows the Patrick the technique for bubble-blowing, there are two red corals in the background - one on his right and one on his left. Later, when he shows Squidward the technique the red coral on the left side of the screen disappears.
Continuity: In the scene where Squidward complains to Spongebob about the construction noise from his stand, Squidward's porthole in the background is black, but from the interior there is a light on (Note: this also happens in every other shot of his house.
Continuity: SpongeBob takes off his ripped pants, and throws them on the ground. His shirt sleeves are perfectly intact. Next, Sandy and Larry are shown playing volleyball. When SpongeBob is shown again, his pants are still gone, and so are his shirt sleeves.
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