Directed by: Peter Farrelly, Bobby Farrelly
Starring: Bill Murray, Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood
Genres: Action, Animated, Comedy, Crime, Drama, Romance, Thriller
Question: If Frank got Anthrax by eating the egg in the monkey's mouth, shouldn't that monkey have been dead anyway?
Question: What happened to Shane's mom? In one scene we learn that she died because she was sick but what did she have that caused her to die?
Answer: Just like Frank, Shane's mom never ate healthily. Instead, like Frank, she probably just ate whatever she wanted, so she most likely died from a heart attack from eating unhealthy foods or from obesity.
Continuity mistake: When Drix freezes the witness from the ship, he says it will take a few days to wear off. Not even a day later it wears off and the witness is back to normal and runs off only to be frozen again later.
Osmosis: We were so poor, we lived off peanut butter and cellulite sandwiches! You ever try to blow-dry your hair with a fart?
Drix: OK, I get it. You were poor.
Osmosis: You bet I was! You ever try to make a snowman out of toilet paper cling-ons? Now that's poor!
Drix: OK, please, you're going to make me vomit!
Osmosis: Vomit? We couldn't afford no vomit; that's for rich folk.
Drix: Excuse me while I wipe my eyes.
Osmosis: Oh, you wanna talk about wiping?
Drix: No.
Trivia: In the widely released version of Osmosis Jones in the background of the opening chase scene, a remix of Foreigner's 'Hot Blooded' plays, but in the VHS release it plays Electric Avenue by Eddy Grant.
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Answer: We are never told that the monkey was sick with the disease. The egg does fall out of the monkeys mouth and onto the ground where the virus could have easily been on the ground and it just happened to come into contact with the egg.