Continuity: When Eddie goes to meet Maroon with his accusations, Maroon is holding a distinctively brass colored gun. When Eddie attacks him, the gun is released by Maroon, and it instantly cuts to a shot of Eddie on top of him, an identical gun in hand. Then when they get up, Eddie tosses the gun aside. When Doom shoots Maroon through the window, Eddie dives for cover and once again the gun is amazingly in his hand.

Revealing: Hoskins and Maroon break the news to Roger Rabbit, and Maroon gives Roger a drink. When he pours the drink you can see a clear plug in the neck of the bottle, and right before Roger Rabbit drinks you can see there is nothing in the glass.

Other: When Eddie sits on the bench and the hippo sits down, you can see Eddie bounce off the bench before the bench even moves.

Continuity: When Eddie pours out his whisky, the way he holds the bottle changes between shots.

Continuity: Near the end in the Acme Factory, the weasels tunnel through the wall and say "Toontown is on the other side of the world, boss". Understandable because of the portal link between the two "dimensions". But while the wall they're tunneling through seems to only have about ten layers of bricks, when the Red Car crashes through it, it alternates between one layer of bricks to three and back and forth.

Continuity: When Eddie is on Maroon's office pouring himself some bourbon, Dumbo shows up and scares Eddie, who throws himself on the ground. The camera then shows him and his empty glass, and the ground is dry. Where did the bourbon go?

Continuity: When Judge Doom is about to dunk the squeaky shoe into the Dip, it seems to stick itself in for him, even though it looks rather scared.

Other: At the beginning of the movie, when Roger is begging the director to give him another chance and keeps grabbing the bottom of the director's jacket that is in the director's hand, at one point the bottom of the jacket leaps into Roger's hand before he actually grabs it.