Quite a few pop culture icons appear in this film such as Ron Jeremy who plays the bartender, Rob Halford of Judas Priest who plays the porn store clerk, Debbie Harry the lead vocalist of Blondie who plays the neighbor and of course Billy Corgan of the Smashing Pumpkins who plays the doctor.

Billy Corgan who sings most of the movies songs has a cameo playing the doctor.

This movie is about methamphetamines. But this movie is similar to Requiem for a Dream in its portrayal of drug use. The makers must have noticed this, because they poke fun at the similarity in one instance. The Cook is in the porn shop, and he buys a movie, and its name is Rectum for a Dream.