This was Eric Balfour's first appearance as Milo Pressman since Day 1 - 3:00pm-4:00pm. In-universe, Pressman's last appearance was more than nine years before.

In Series 6 (Day 6), Eddie Izzard was originally cast as Darren McCarthy, but only filmed for one day and then pulled out due to a 'scheduling conflict'.

Wayne Palmer was the only president who was actually seen in the Oval Office during his term in office.

On the DVD, the writers revealed that they originally planned for a subplot regarding Josh Bauer's paternity. Originally the idea was that he would turn out to be Jack's son, but this idea was later changed into him being Philip Bauer's son. This idea wasn't scrapped until they wrote the final episode of the season. Philip Bauer was going to reveal the truth to Josh at the oil rig, but the idea was abandoned because it would add too much drama to an already dramatic situation.

With the 12,000 people killed in the nuclear blast, in addition to the hundreds of casualties from the previous 11 weeks, Abu Fayed is the show's most successful mass murderer.