Corrected entry: It's very hard to believe that someone who takes as much medication as Sara could have so much energy and be able to act as if nothing was wrong with her, at least during the first part of the movie (until the script calls for her to act more realistically). Also, many medications cause considerable weight gain as a side effect. Sara wouldn't be able to look like a thin gorgeous supermodel while taking all those pills.
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Correction: She could be taking medications that actually give her energy, or at least make her seem normal. Many medications (not to mention just having terminal cancer) cause considerable weight LOSS.
Myridon