Continuity: In the scene where Cameron Diaz and her husband are talking to the doctor in a flashback, her hair repeatedly goes from behind her shoulders to in front. it is especially obvious when at one point she turns towards her husband and her hair completely changes position.
Great sites
Mistakes
In the scene where Anna visits Campbell for the first time, he looks at her medical records, and in the close up it shows Anna's birth date as 05/16/1990, but in the scene where Kate is showing her mother the scrapbook she's made it contains a picture which shows that Kate's birth date is 08/22/1990, which makes Anna somehow 3 months older than her supposedly elder sister. See more...
My Sister's Keeper mistakes
Revealing: When Sara is shaving her hair in front of the mirror, you can see the "join" between her forehead and the "skull cap" she's wearing under her hair.
Factual error: In the scene where Anna visits Campbell for the first time, he looks at her medical records, and in the close up it shows Anna's birth date as 05/16/1990, but in the scene where Kate is showing her mother the scrapbook she's made it contains a picture which shows that Kate's birth date is 08/22/1990, which makes Anna somehow 3 months older than her supposedly elder sister.