Mistakes
In many of the non-CG generated snake shots, what appears to be a very venomous coral snake is in fact either a scarlet king snake or a California mountain king snake (depending on the shot). These are much safer, non-venomous alternatives for filming with the actors. Look for the ordering of the colored bands (red/black=venom lack, red/yellow=kill a fellow). See more...
Trivia
During filming, Samuel L. Jackson did not come into contact with any live snakes, because a contract clause prevented snakes from being within 25 feet (8 m) of the actor. See more...
Movie Mistakes blog
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Neville Flynn: Enough is enough! I have had it with these motherfucking snakes on this motherfucking plane!