Deliberate mistake: Near the beginning of the film, when Aeon breaks into the security system, the final shot of Aeon's face as she takes out the first set of guards shows her hair parting on the wrong side, revealing a flipped shot.
Continuity mistake: In the Aeon vs Sithandra fight, Aeon's hair parting is on the left. But once the fight begins it suddenly switches to the right, only to return to the left again when Aeon knocks Sithandra down from the ceiling.
Production was suspended for over a month whilst Charlize Theron recovered from a neck injury she suffered doing stunt work on the tenth day of shooting. She was in hospital for five days and needed about six weeks of physiotherapy to recover.